Phospho-GAB1 (Tyr627) Antibody detects endogenous levels of GAB1 only when phosphorylated at Tyrosine 627. Grb2-associated binding protein 1 is a member of the IRS-1-like multisubstrate docking protein family. Contains an N-terminal pleckstrin homology (PH) domain and several proline-rich SH3 domain-binding sequences.