Phospho-mTOR (Thr2446) Antibody detects endogenous levels of mTOR only when phosphorylated at Threonine 2446. an atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
