- 中文名称
72 kDa Inositol Polyphosphate 5-Phosphatase (INPP5E) Antibody
- 英文名字
- 72 kDa Inositol Polyphosphate 5-Phosphatase (INPP5E) Antibody
- 供应商
- Abbexa
- 产品货号
- abx003688
- 产品报价
- ￥20ul ￥50ul ￥100ul ￥200ul
- 产品说明书
- 点击查看
- 购买方式
- 产品新闻
- 背景资料
- INPP5E Antibody is a Rabbit Monoclonal antibody against INPP5E. The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. Studies of the mouse counterpart suggest that this protein may hydrolyze phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,5-bisphosphate on the cytoplasmic Golgi membrane and thereby regulate Golgi-vesicular trafficking. Mutations in this gene cause Joubert syndrome; a clinically and genetically heterogenous group of disorders characterized by midbrain-hindbrain malformation and various associated ciliopathies that include retinal dystrophy, nephronophthisis, liver fibrosis and polydactyly.
- 应用类型
- WB, IHC, IF/ICC, IP
- 免疫原
- INPP5E
- 来源宿主
- 反应性
- 保存建议
- 其他
- Abbexa
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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