- 中文名称
Cyclic AMP-Dependent Transcription Factor ATF-6 Alpha (ATF6) Antibody
- 英文名字
- Cyclic AMP-Dependent Transcription Factor ATF-6 Alpha (ATF6) Antibody
- 供应商
- Abbexa
- 产品货号
- abx000591
- 产品报价
- ￥询价/20ul ￥询价/50ul ￥询价/100ul ￥询价/200ul
- 产品说明书
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- 购买方式
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- 产品新闻
- 背景资料
- ATF6 Antibody is a Rabbit Polyclonal antibody against ATF6. This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis.
- 应用类型
- WB
- 免疫原
- ATF6
- 来源宿主
- 兔
- 反应性
- 人，小鼠
- 保存建议
- 建议收到该Cyclic AMP-Dependent Transcription Factor ATF-6 Alpha (ATF6) Antibody产品后，储存温度为-20°C。避免重复冻融
- 其他
- Abbexa总部位于英国剑桥的剑桥科学园,是一家专业的全球抗体供应商和蛋白质供应商,致力于为生命科学、药物开发和生物技术领域的科学家和研究者提供最佳的客户体验和高质量的产品。产品涵盖一抗、二抗、蛋白质、ELISA试剂盒、酶以及其他用于研究的试剂盒和工具。无论您是进行学术研究,药物开发,疾病研究还是其它生物学研究,Abbexa的单克隆抗体,多克隆抗体,蛋白质和生物试剂均旨在促进您的研究。如果很难找到合适的抗体来满足您的需求,Abbexa还提供了定制蛋白质,肽和抗体的生产渠道。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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