GYY4137 is a water soluble, slow releasing hydrogen sulfide (H2S) donor. Facilitates Exhibits vasodilator and antihypertensive activity. Activity causes slow dilation of blood vessels in vitro and in vivo. Oxidative stress-induced cell death inhibitor. Shows novel anti-cancer effects in vitro and in vivo.
Background:
H2S, a well known and pungent gas, has been found to be synthesised enzymatically in mammalian and human tissues and as a result has attracted substantial interest as an endogenous gaseous mediator and potential target for pharmacological manipulation. Studies in animals and humans have shown H2S to be involved in diverse physiological and pathophysiological processes, such as learning and memory, neurodegeneration, regulation of inflammation and blood pressure (vasodilator), and metabolism.
产品描述
Water soluble, slow releasing hydrogen sulfide (H2S) donor
