20S immunoproteasome:
High integrity, high purity human cell line derived 20S immunoproteasome complex. Characterised by SDS-PAGE and fluorogenic peptide substrate activity assay to determine 20S immunoproteasome purity and chymotrypsin-like, trypsin-like and caspase-like activities. Degrades peptide substrates but not polyubiquitinated proteins (ubiquitin independent activity).
Background:
When cells are stimulated with pro-inflammatory cytokines, such as interferon gamma (IFN-
