- 中文名称
UbcH3 蛋白(人) (His标签)
- 英文名字
- UbcH3 protein(human) (His tag)
- 供应商
- Viva Bioscience
- 产品货号
- VB2478-100
- 产品报价
- ￥3250/100ug
- 产品说明书
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- 购买方式
- 产品新闻
- 背景资料
- UbcH3, also known as UBE2R1, is a member of the ubiquitin E2 conjugating enzyme family, essential components of the ubiquitin cascade.
The selectivity of the ubiquitin cascade for a particular substrate protein relies on the interaction between the E2 conjugating enzyme (of which a cell contains relatively few) and an ubiquitin E3 ligase, of which over 600 have been identified to date. The specific E2-E3 pair required for ubiquitination of a particular substrate protein in vivo may also control the type of ubiquitin modification (mono-, multi-, poly-ubiquitin), the exact substrate lysine residue(s) to be modified and, in the case of polyubiquitination, the chain length and lysine linkage type.
UbcH3 plays an essential role in promoting the G1-S-phase transition of the eukaryotic cell cycle, as process regulated by the casein kinase type II (CK2) mediated phosphorylation of UbcH3.
Recombinant human UbcH3 protein expressed with a N-terminal His-tag. Protein has utility in ubiquitination reactions, polyubiquitin chain synthesis, identification of substrate specific E2-E3 pairs and determination of E2 polyubiquitin linkage specificity.
- 序列
- P49427
- 来源宿主
- 溶解建议
- 1 mg/mL
- 保存建议
- 其他
- Ӣ
- 注意
-
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