Specific and potent autophagy inhibitor. Promotes the degradation of Vps34 PI3 kinase complexes by inhibiting two ubiquitin specific peptidases, USP10 and USP13, that target the Beclin1 subunit of Vps34 complexes.
产品描述
Specific and potent autophagy inhibitor (autophagosome formation). Promotes Vps34 PI3 kinase complex degradation through USP10 and USP13 inhibition