Specific reversible inhibitor of protein translocation from endoplasmic reticulum (ER) to Golgi apparatus leading to an accumulation of proteins inside the ER resulting in ER stress / unfolded protein response and ultimately autophagy activation or induction of apoptosis. Blocks binding of ADP-ribosylation factor to the Golgi apparatus and inhibits GDP-GTP exchange. Utility in the study of protein transportand Induces apoptosis. Activates sphingomyelin metabolism. Cell permeable.
产品描述
ER stress / unfolded protein response inducer. Autophagy activator
