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中文名称

Thyroid Peroxidase, Human, BioAssay ELISA Kit (TPO, TMA, Thyroid Microsomal Human Antigen)

英文名字
Thyroid Peroxidase, Human, BioAssay ELISA Kit (TPO, TMA, Thyroid Microsomal Human Antigen)
供应商
USBiological
产品货号
T5399-02B
产品报价
¥1/1Kit
产品说明书
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背景资料
产品描述
The United States Biological Thyroid Peroxidase, Human, BioAssay ELISA Kit is intended for the detection and semi-quantitation of antibodies to microsomal in human serum. The assay is to be used to detect antibodies in a single serum specimen. Autoimmune thyroid disease is characterized by the presence of circulating autoantibodies directed to thyroid antigens. Hashimoto and Graves diseases are the best known of these diseases. The majority can be diagnosed by clinical presentation and their antibody profiles to thyroglobulin and thyroid microsomes. Thyroglobulin is a water soluble glycoprotein that is involved in the storage and synthesis of thyroid hormones. The thyroid microsomal antigen has been shown to be the enzyme thyroid peroxidase (TPO). Antibodies to thyroglobulin and or microsomal antigen are present in most patients with goitrous thyroiditis (Hashimoto disease), atrophic thyroiditis (myxedema) and about 70-90% of Graves disease. Antibodies are also found in about half of the patients with primary hypothyroidism and thyrotoxicosis, and 10-20% of patients with simple goiters and thyroid tumors. There is also a relationship between thyroid antibodies and diabetes mellitus. Thyroid autoantibodies are present in about 6-7% of normals and their incidence increases with age. Classically, autoantibodies to thyroid antigens are detected by precipitation reactions, hemag- glutination and by immunoflourescence. However the tests are subjective and lack high sensitivity. ELISAs combine greater sensitivity, objective reading and ease of use. ELISAs have been developed and validated for detecting autoantibodies to thyroid antigens.Kit Components:Each kit contains the following components in sufficient quantities to perform the number of tests indicated on the package label.1. Microtiter Plate: 1x96 wells2. Sample Diluent: 1x30ml3. Positive Control, High: 1x400ul4. Calibrator: 1x400ul5. Negative Control: 1x400ul6. Positive Control, Low: 1x400ul7. IgG, IgA, IgM (HRP) Goat x human: 1x15ml8. Wash Buffer, 20X: 1x50ml9. Tetramethylbenzidine (TMB): 1x15ml10. Stop Solution: 1x15mlStorage and Stability: Store all components at 4°C. Stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
产品特点
针对Thyroid Peroxidase, Human, BioAssay ELISA Kit (TPO, TMA, Thyroid Microsomal Human Antigen)该产品的特点优势,欢迎查阅官网提供的产品说明书。
保存建议
建议收到Thyroid Peroxidase, Human, BioAssay ELISA Kit (TPO, TMA, Thyroid Microsomal Human Antigen)产品后将其置于4°C保存。
其他
Usbiological公司是美国著名的抗体和生化试剂供应商,生产世界上种类最多的抗体,用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品,为科研用户提供了诸多超值选择。
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