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中文名称

Tau, Total, Human (Tau Protein, Microtubule-associated Protein, MAP) BioAssay ELISA Kit

英文名字
Tau, Total, Human (Tau Protein, Microtubule-associated Protein, MAP) BioAssay ELISA Kit
供应商
USBiological
产品货号
T1034-25
产品报价
¥1/96Tests
产品说明书
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背景资料
产品描述
Tau, Total, Human (Tau Protein, Microtubule-associated Protein, MAP) BioAssay ELISA Kit is used for the quantitative determination of human total Tau protein. Tau is a microtubule associated protein found predominantly in neuronal axons of vertebrate brain. Tau protein is highly soluble and normally attached to axonal microtubules. Tau stabilizes the microtubules and makes them rigid. Tau interacts with actin in the cytoskeleton and neuronal outgrowth, anchors enzymes such as protein kinases and phosphatases, and regulates intracellular vesicle transport. Tau phosphorylation regulates both normal and pathological functions of this protein. Tau, in its hyperphosphorylated form, is the major component of paired helical filaments (PHFs), the building block of neurofibrillary lesions in Alzheimer’s disease (AD). Hyperphosphorylation impairs the microtubule binding function of tau, resulting in the destabilization of microtubules in AD brains, ultimately leading to neuronal degeneration. Deposition of filamentous tau is implicated in other neurodegenerative diseases including cortical basal degeneration (CBD), progressive supranuclear palsy (PSP), Pick’s disease and certain forms of Parkinson’s disease.Sensitivity: <10pg/mlRange: 31.2-2000pg/mlIncubation Time: 4 hoursSample Size: 50ulAccuracy:Inter-assay CV: ≤10%Intra-assay CV: ≤8%Kit Components:T1034-25A: Microtiter Plate 1x96 wells Coated with human Tau antibodyT1034-25B: Standard 2x1 vial T1034-25C: Standard Diluent Buffer. 1x25ml T1034-25D: Detection Antibody 1x11ml T1034-25E: Pab (HRP), 100X 1x125ulT1034-25F: HRP Diluent 1x25mlT1034-25G: Wash Buffer, 25X 1x100mlT1034-25H: TMB 1x25ml T1034-25J: Stop Solution 1x25mlStorage and Stability:Store all components at 4°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
产品特点
针对Tau, Total, Human (Tau Protein, Microtubule-associated Protein, MAP) BioAssay ELISA Kit该产品的特点优势,欢迎查阅官网提供的产品说明书。
保存建议
建议收到Tau, Total, Human (Tau Protein, Microtubule-associated Protein, MAP) BioAssay ELISA Kit产品后将其置于4°C保存。
其他
Usbiological公司是美国著名的抗体和生化试剂供应商,生产世界上种类最多的抗体,用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品,为科研用户提供了诸多超值选择。
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