Oxidative Stress/ Damage->Protein Oxidation / Nitration->Advanced Glycation End Products->AGE Assays and Reagents->AGE Competitive ELISA
应用类型
Advanced glycation end products (AGE) are formed during the Maillard reaction where reducing carbohydrates react with lysine side chains and N-terminal amino groups of various macromolecules, particularly proteins (Figure 1). The advanced glycation end products can adversely affect the fuction of these macromolecules. One of the most prevalent advanced glycation end products, N-epsilon-(Carboxymethyl) Lysine, has been implicated in oxidative stress and vascular damage. Our OxiSelect™ AGE Competitive ELISA kit is designed for rapid detection and quantitation of advanced glycation end product protein adducts. The quantity of AGE adduct in protein samples is determined by comparing its OD with that of a known AGE-BSA standard curve.
免疫原
Detect advanced glycation end product formation as low as 0.5 µg/mL
