- 中文名称
Syk, phosphorylated BioAssay Sample Kit
- 英文名字
- Syk, phosphorylated BioAssay Sample Kit
- 供应商
- USBiological
- 产品货号
- S9100-20
- 产品报价
- ￥1/4x20ul
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- 产品描述
- Syk, one of the well known protein tyrosine kinases, is widely expressed and plays an important role in intracellular signal transduction in hematopoietic cells (1–3). Syk has been shown to interact with immunoreceptor tyrosine–based activation motifs (ITAMs) located in the cytoplasmic domains of immune receptors (4). It couples the activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation and phagocytosis (4). There is also evidence of a role for Syk in nonimmune cells, and Syk may be a potential tumor suppressor in human breast carcinomas (5). Tyr323 is a negative regulatory phosphorylation site within the SH2-kinase linker region in Syk. Phosphorylation of Tyr323 provides a direct binding site to the TKB domain of Cbl (6,7). The Tyr352 residue in Syk is involved in the association of PLC-g1 (8). Tyr525/526 are located in the activation loop of Syk kinase domain, phosphorylation of Tyr525/526 of human Syk (equivalent to the Tyr519/520 of mouse Syk) is essential for Syk function (9). Phospho-Syk Sampler Kit provides an economical means to evalute the activation status of Syk, including the phosphorylation of Tyr323, Tyr352, and Tyr525/526. The control Syk Antibody is also included. The kit contains enough primary and secondary antibodies for two mini-blot experiments.
- 产品特点
- 针对Syk, phosphorylated BioAssay Sample Kit该产品的特点优势，欢迎查阅官网提供的产品说明书。
- 保存建议
- 建议收到Syk, phosphorylated BioAssay Sample Kit产品后将其置于-20°C保存。
- 其他
- Usbiological公司是美国著名的抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品，为科研用户提供了诸多超值选择。
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- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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