- 中文名称
SAPK (JNK) Pathway, phosphorylated BioAssay Sample Kit
- 英文名字
- SAPK (JNK) Pathway, phosphorylated BioAssay Sample Kit
- 供应商
- USBiological
- 产品货号
- S0097
- 产品报价
- ¥1/4x20ul

- 产品说明书
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- 产品新闻

- 背景资料
- USBiological品牌是全球有名的抗原抗体和生化试剂供应商,生产世界上种类最多的抗体,用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理,是行业中少有的致力于服务客户,帮助客户,且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应,专业的产品和解决方案支持,稳健快捷的交货周期,优质放心的售后服务。我们致力于为您提供有价值的产品和服务,在意您的成功!
- 产品描述
- The stress-activated protein kinase/Junterminal kinase SAPK/JNK is potently and preferentially activated by a variety of environmental stresses including UV and g radiation, ceramides, inflammatory cytokines and, in some instances, by growth factors and GPCR agonists. As with the other MAPKs, the core signaling unit is composed of an MAPKKK, typically MEKK1–4, or a member of the mixed lineage kinases (MLK) that would phosphorylate and activate MKK4/7, the SAPK/JNK kinase. Stress signals are delivered to this cascade by members of small GTPases of the Rho family (Racs, Rhos, cdc42s). Both Rac1 and cdc42 mediate the stimulation of MEKKs and MLKs. Alternatively, MKK4/7 can be activated in a pathway independent of small GTPases via stimulation of a member of germinal center kinase (GCK) family. There are three SAPK/JNK genes with further diversification from alternative splicing. SAPK/JNK, when active as a dimer, can translocate to the nucleus where it regulates transcription through its effects on c-Jun and ATF-2 and other transcription factors. The Phospho-SAPK/JNK Pathway Sampler Kit provides a fast and economical means to evaluate the activation status of SAPK/JNK pathways, including phosphorylated SEK1/MKK4, SAPK/JNK, ATF-2 and c-Jun. The kit includes enough primary and secondary antibodies to perform four mini-blot experiments.
- 产品特点
- 针对SAPK (JNK) Pathway, phosphorylated BioAssay Sample Kit该产品的特点优势,欢迎查阅官网提供的产品说明书。
- 保存建议
- 建议收到SAPK (JNK) Pathway, phosphorylated BioAssay Sample Kit产品后将其置于-20°C保存。
- 其他
- Usbiological公司是美国著名的抗体和生化试剂供应商,生产世界上种类最多的抗体,用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品,为科研用户提供了诸多超值选择。
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- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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