The herpes simplex (HSV) (also known as cold sore, night fever or fever blister) is a virus that causes a contagious disease. There are two main types of Herpes Simplex Virus (HSV) , 1 and 2; and they belong to a family that includes Epstein-Barr virus (EBV) and Varicella zoster (chicken pox) virus. HSV1 and HSV2 are extremely difficult to distinguish from each other. The HSV-1 strain generally appears in the orafacial organs. HSV2 usually resides in the sacral ganglion at the base of the spine. These viruses have a large DNA genome, capsid, and a lipid bilayer membrane derived from the nuclear membrane of the last host. These viruses are capable of entering a latent phase where the host shows no visible sign of infection. Envelope glycoprotein C (gC) and glycoprotein B (gB) bind to cell surface partials heparin sulfate. Receptor binding protein glycoprotein D (gD) binds to HVEM, nectin-1, and 3-O sulfated heparin sulfate forming complexes with glycoprotein H (gH) and glycoprotein (gL) creating an entry pore for the viral capsid.
应用类型
Immunohistochemistry,
免疫原
Anti-Herpes Simplex Virus Type I Antibody was produced in rabbit by repeated immunizations with detergent-solubilized herpes simplex virus (HSV) type 1 infected cells.
来源宿主
Rabbit
反应性
Herpesvirus
保存建议
Store at 2-8°C. This antibody is suitable for use until the expiration date when stored at 2-8°C. Do not use product after the expiration date printed on vial. If reagents are stored under conditions other than those specified here, they must be verified by the user. Diluted reagents should be used promptly. Unused portions of antibody preparation should be discarded after one day. The presence of precipitate or an unusual odor indicates that the antibody is deteriorating and should not be used.
