该Phospho-IRS1 (Tyr896) Polyclonal Antibody. May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.
应用类型
WB,ELISA
免疫原
Synthesized peptide derived from human IRS-1 around the phosphorylation site of Tyr896
