该Phospho-Glucocorticoid Receptor (Ser211) Polyclonal Antibody. Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation.
应用类型
WB,IHC-p,ELISA
免疫原
Synthesized peptide derived from human GR around the phosphorylation site of Ser211
