该PRAME Polyclonal Antibody. This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.
应用类型
IF
免疫原
Recombinant fusion protein of human PRAME (NP_996839.1).
