该SUV39H1 Polyclonal Antibody. This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants.
应用类型
IF
免疫原
Recombinant fusion protein of human SUV39H1 (NP_003164.1).
