该ERLIN1 Polyclonal Antibody. The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62.
应用类型
IHC
免疫原
Recombinant fusion protein of human ERLIN1 (NP_006450.2).
