该Cleaved-CASP1 (D210) Polyclonal Antibody. Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
应用类型
WB,IHC-p,IF,ELISA
免疫原
Synthesized peptide derived from the Internal region of human Caspase-1