该BUB1B Polyclonal Antibody. This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.
应用类型
IHC,IF
免疫原
Recombinant fusion protein of human BUB1B (NP_001202.4).
