- 中文名称
Rheumatoid Factor, Human, BioAssay ELISA Kit (RF)
- 英文名字
- Rheumatoid Factor, Human, BioAssay ELISA Kit (RF)
- 供应商
- USBiological
- 产品货号
- R1997-05J
- 产品报价
- ￥1/1Kit
- 产品说明书
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- 产品新闻
- 背景资料
- USBiological品牌是全球有名的抗原抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理，是行业中少有的致力于服务客户，帮助客户，且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应，专业的产品和解决方案支持，稳健快捷的交货周期，优质放心的售后服务。我们致力于为您提供有价值的产品和服务，在意您的成功！
- 产品描述
- Intended Use:Rheumatoid Factor, Human, BioAssay ELISA Kit (RF) is intended for the detection of IgM antibodies in serum to RF antigen.Rheumatoid arthritis (RA) is a chronic inflammatory disease of unknown etiology. Rheumatoid arthritis is a systemic disease characterized by chronic proliferation and inflammation of joint cartilage and supporting structures. RA is mainly defined by clinical criteria, in which systematic pathogenetic studies have been hampered by doubts about the presence of common pathogenetic mechanisms and the relative lack of unique laboratory findings. IgG rheumatoid factor has been reported to be present in sera of patients with rheumatoid arthritis both with and without IgM rheumatoid factor activity.RFs are immunoglobulins of any isotype with antibody activity directed against antigenic sites on the Fc portion of IgG molecules. Because of its pentavalent structure and ability to cross-link immunoglobulin G antigen, IgM-RF is the main isotype identified by clinically available diagnostic assays for RF detection. Rheumatoid factors may exist as the mu, gamma, alpha, and epsilon isotypes.Rheumatoid factors are found in 1 to 4% of the general population. RFs are present in 75% of adult patients with the highest incidence of rheumatoid factors occurring in persons over 65 years of age and nearly all patients with Felty and Sjogren syndrome. The clinical correlation of an elevated rheumatoid factor should be interpreted cautiously. Increased titers may accompany a variety of acute immune responses, particularly viral infections and a number of other diseases (e.g., infectious mononucleosis, tuberculosis, leprosy, various parasitic diseases, liver disease, sarcoidosis, and lymphoproliferative syndromes). The earliest tests and those still most widely used rely on the agglutinating properties of the IgM class of rheumatoid factors. Sensitized sheep red blood cell and latex agglutination tests have been developed and routinely employed. These assays are most sensitive for the detection of RF that is of the IgM isotype because of its multivalent structure. These tests provide a dilution which is difficult to standardize and have laborious processing and poor reproducibility. Enzyme immunoassays are more sensitive than agglutination and very specific due to use of purified antigen.Kit Components:R1997-05J1: Microtiter Strips, 1x96 wellsR1997-05J2: Sample Diluent, 1x30ml, 0.1% ProclinR1997-05J3: Positive Control, 1.6-3.9, 1x400ul, <0.1% sodium azideR1997-05J4: Calibrator CF:0.55, 1x400ul, <0.1% sodium azideR1997-05J5: Negative Control, 0.0-0.8, 1x400ul <0.1% sodium azideR1997-05J6: IgG (HRP) Goat anti-human, 1x16ml, 0.1% ProclinR1997-05J7: Wash Buffer, 20X, 1x50ml, 0.1% ProclinR1997-05J8: Substrate (TMB), 1x15mlR1997-05J9: Stop Solution, 1N H2SO4, 1x15mlStorage and Stability: Store all components at 4°C. Stable for 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- 产品特点
- 针对Rheumatoid Factor, Human, BioAssay ELISA Kit (RF)该产品的特点优势，欢迎查阅官网提供的产品说明书。
- 保存建议
- 建议收到Rheumatoid Factor, Human, BioAssay ELISA Kit (RF)产品后将其置于4°C保存。
- 其他
- Usbiological公司是美国著名的抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品，为科研用户提供了诸多超值选择。
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- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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