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中文名称

TCRgd 抗体 [TCR-1] (Biotin)

英文名字
TCRgd Antibody [TCR-1] (Biotin)
供应商
ProSci
产品货号
PSI-99-221
产品报价
¥询价/0.5mg
产品说明书
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产品新闻
背景资料
The monoclonal antibody TCR-1 precipitates a heterodimer of Mr 90 kDa (two bands of Mr 50 kDa and 40 kDa upon reduction) on chicken peripheral blood T cells. Deglycosylation of the heterodimer yields two polypeptides of Mr 35 kDa and 32 kDa. Unlike human and mouse in which gammadelta cells comprise a minor subset of T lymphocytes in the circulation, the chicken has a relatively large subset of gammadelta T cells. The frequency of TCRgammadelta cells is typically 20-25% of the total blood T cells but may reach approximately 50% in chickens of six- months of age. The majority of TCRgammadelta+ cells in the thymus and blood are CD4-CD8- although a small subset of them may express CD8 or CD4 coreceptors. However, when the TCRgammadelta+ cells migrate into the spleen and intestine most of them begin to express CD8. Although the biological function of gammadelta T cells is unclear, they are clearly capable of cytotoxic activity in vitro. The CD8+ gammadelta T cells may also be involved in down-regulation of the immune response. They cannot, however, induce a graft-vs-host (GVH) reactions.
应用类型
Flow
免疫原
Outbred chicken thymocytes and Ig-negative blood lymphocytes
来源宿主
小鼠
反应性
鸡, Milk Snake
保存建议
Store vial at 2-8˚C
其他
ProSci Incorporated于1998年成立于美国加州圣地亚哥市,从事抗体等科研试剂的研发、生产和销售。产品涵盖了细胞凋亡、信号转导、免疫、肿瘤、细胞生物、神经生物、传染病等领域。ProSci拥有超过30000种单克隆抗体和多克隆抗体。ProSci的抗体大都经免疫亲和层析纯化,具有高纯度、高亲和力、特异性强等特点,所有的ProSci抗体都经过了严格的验证测试和质量控制,已保证高质量的产品。此外,ProSci还提供标记二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽等产品与抗体配套使用。
注意
该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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