- 中文名称
IL-36 alpha 重组蛋白
- 英文名字
- IL-36 alpha Recombinant Protein
- 供应商
- ProSci
- 产品货号
- PSI-91-058
- 产品报价
- ￥询价/0.05mg
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- Human Interleukin-36 alpha (IL-36 alpha) is a secreted cytokine that belongs to the Interleukin 1 cytokine family. IL-36 alpha is expressed in the immune system and the fetal brain, but not in other tissues or multiple hematopoietic cell lines. IL-36 alpha is the only IL-1 family member found to be expressed on T-cells. IL-36 alpha and IL-1F8 are involved in the regulation of adipose tissue gene expression. Importantly, IL-36 alpha inhibits PPAR gamma expression, which may lead to a reduction in adipocyte differentiation suggesting metabolic effects of this cytokine. IL-36 alpha, along with IL-1F8 and IL-1F9, has been shown to act as an agonist by activating the pathway involving NFκB and MAPK in an IL-1Rrp2 dependent manner. This suggest that IL-36 alpha may signal in a similar fashion to IL-1 and IL-18 in having a binding receptor which upon ligation, recruits a second receptor as a signaling component, forming an active heterodimeric receptor complex.
- 序列
- Met1-Phe158
- 来源宿主
- 大肠杆菌
- 溶解建议
- 艾美捷温馨提示:开盖前,请先离心。厂家建议您，按照该货号产品的说明书中要求的方式进行溶解和使用。
- 保存建议
- Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
- 其他
- ProSci Incorporated于1998年成立于美国加州圣地亚哥市,从事抗体等科研试剂的研发、生产和销售。产品涵盖了细胞凋亡、信号转导、免疫、肿瘤、细胞生物、神经生物、传染病等领域。ProSci拥有超过30000种单克隆抗体和多克隆抗体。ProSci的抗体大都经免疫亲和层析纯化,具有高纯度、高亲和力、特异性强等特点,所有的ProSci抗体都经过了严格的验证测试和质量控制,已保证高质量的产品。此外,ProSci还提供标记二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽等产品与抗体配套使用。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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