- 中文名称
YAP (phospho Ser127) 抗体
- 英文名字
- YAP (phospho Ser127) Antibody
- 供应商
- ProSci
- 产品货号
- PSI-80-002
- 产品报价
- ￥询价/0.1mg
- 产品说明书
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- 购买方式
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- 产品新闻
- 背景资料
- Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Plays a key role to control cell proliferation in response to cell contact.
- 应用类型
- WB
- 免疫原
- YAP (phospho Ser127) antibody was raised against a peptide sequence around phosphorylation site of serine127 (A-H-S (p)-S-P) derived from Human YAP .
- 来源宿主
- 兔
- 反应性
- 人, 小鼠, 大鼠
- 保存建议
- Store antibody at -20˚C for up to one year.
- 其他
- ProSci Incorporated于1998年成立于美国加州圣地亚哥市,从事抗体等科研试剂的研发、生产和销售。产品涵盖了细胞凋亡、信号转导、免疫、肿瘤、细胞生物、神经生物、传染病等领域。ProSci拥有超过30000种单克隆抗体和多克隆抗体。ProSci的抗体大都经免疫亲和层析纯化,具有高纯度、高亲和力、特异性强等特点,所有的ProSci抗体都经过了严格的验证测试和质量控制,已保证高质量的产品。此外,ProSci还提供标记二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽等产品与抗体配套使用。
- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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