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中文名称

FOXA1 抗体

英文名字
FOXA1 Antibody
供应商
ProSci
产品货号
PSI-7255
产品报价
¥询价/0.1mg
产品说明书
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产品新闻
背景资料
FOXA1 Antibody: FOXA1 is one of three members of the FOXA family, a subset of the forkhead family of transcription factors which play vital roles in development. It has also been implicated in the development of a number of other organs including the androgen and estrogen regulated tissues of the breast and prostate. FOXA1 modulates the transcriptional activity of nuclear hormone receptors and regulates apoptosis by inhibiting the expression of BCL-2. It is an essential protein for the transcriptional activity of both androgen receptor (AR) and estrogen receptor-α (ER). FOXA1 plays a pivotal role from early stage cancer through to drug resistant and metastatic disease. FOXA1 is not only an attractive therapeutic target but could potentially function as a novel biomarker.
应用类型
E, WB
免疫原
Rabbit polyclonal FOXA1 antibody was raised against a 17 amino acid peptide near the center of human FOXA1.
The immunogen is located within amino acids 270 - 320 of FOXA1.
来源宿主
反应性
保存建议
FOXA1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
其他
ProSci Incorporated于1998年成立于美国加州圣地亚哥市,从事抗体等科研试剂的研发、生产和销售。产品涵盖了细胞凋亡、信号转导、免疫、肿瘤、细胞生物、神经生物、传染病等领域。ProSci拥有超过30000种单克隆抗体和多克隆抗体。ProSci的抗体大都经免疫亲和层析纯化,具有高纯度、高亲和力、特异性强等特点,所有的ProSci抗体都经过了严格的验证测试和质量控制,已保证高质量的产品。此外,ProSci还提供标记二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽等产品与抗体配套使用。
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