- 中文名称
SEMA4A 抗体
- 英文名字
- SEMA4A Antibody
- 供应商
- ProSci
- 产品货号
- PSI-58-716
- 产品报价
- ¥询价/400ul

- 产品说明书
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- 产品新闻

- 背景资料
- This gene encodes a member of the semaphorin family ofnsoluble and transmembrane proteins. Semaphorins are involved innnumerous functions, including axon guidance, morphogenesis,ncarcinogenesis, and immunomodulation. The encoded protein is ansingle-pass type I membrane protein containing annimmunoglobulin-like C2-type domain, a PSI domain and a sema domain.nIt inhibits axonal extension by providing local signals to specifynterritories inaccessible for growing axons. It is an activator ofnT-cell-mediated immunity and suppresses vascular endothelial growthnfactor (VEGF)-mediated endothelial cell migration and proliferationnin vitro and angiogenesis in vivo. Mutations in this gene arenassociated with retinal degenerative diseases including retinitisnpigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10).nMultiple alternatively spliced transcript variants encodingndifferent isoforms have been identified.
- 应用类型
- WB
- 免疫原
- This SEMA4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the N-terminal region of human SEMA4A.
- 来源宿主
- 兔
- 反应性
- 人, 小鼠
- 保存建议
- Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 其他
- ProSci Incorporated于1998年成立于美国加州圣地亚哥市,从事抗体等科研试剂的研发、生产和销售。产品涵盖了细胞凋亡、信号转导、免疫、肿瘤、细胞生物、神经生物、传染病等领域。ProSci拥有超过30000种单克隆抗体和多克隆抗体。ProSci的抗体大都经免疫亲和层析纯化,具有高纯度、高亲和力、特异性强等特点,所有的ProSci抗体都经过了严格的验证测试和质量控制,已保证高质量的产品。此外,ProSci还提供标记二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽等产品与抗体配套使用。

- 注意
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