- 中文名称
NR1I3 抗体
- 英文名字
- NR1I3 Antibody
- 供应商
- ProSci
- 产品货号
- PSI-57-837
- 产品报价
- ¥询价/400ul

- 产品说明书
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- 购买方式
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- 产品新闻

- 背景资料
- This gene encodes a member of the nuclear receptornsuperfamily, and is a key regulator of xenobiotic and endobioticnmetabolism. The protein binds to DNA as a monomer or a heterodimernwith the retinoid X receptor and regulates the transcription ofntarget genes involved in drug metabolism and bilirubin clearance,nsuch as cytochrome P450 family members. Unlike most nuclearnreceptors, this transcriptional regulator is constitutively activenin the absence of ligand but is regulated by both agonists andninverse agonists. Ligand binding results in translocation of thisnprotein to the nucleus, where it activates or represses target genentranscription. These ligands include bilirubin, a variety ofnforeign compounds, steroid hormones, and prescription drugs.nMultiple transcript variants encoding different isoforms have beennfound for this gene.
- 应用类型
- WB
- 免疫原
- This NR1I3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-183 amino acids from the Central region of human NR1I3.
- 来源宿主
- 兔
- 反应性
- 人
- 保存建议
- Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 其他
- ProSci Incorporated于1998年成立于美国加州圣地亚哥市,从事抗体等科研试剂的研发、生产和销售。产品涵盖了细胞凋亡、信号转导、免疫、肿瘤、细胞生物、神经生物、传染病等领域。ProSci拥有超过30000种单克隆抗体和多克隆抗体。ProSci的抗体大都经免疫亲和层析纯化,具有高纯度、高亲和力、特异性强等特点,所有的ProSci抗体都经过了严格的验证测试和质量控制,已保证高质量的产品。此外,ProSci还提供标记二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽等产品与抗体配套使用。

- 注意
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