- 中文名称
NFKBIB 抗体
- 英文名字
- NFKBIB Antibody
- 供应商
- ProSci
- 产品货号
- PSI-57-267
- 产品报价
- ¥询价/400ul

- 产品说明书
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- 购买方式
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- 产品新闻

- 背景资料
- NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to RELn(MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form thenNFKB complex. The NFKB complex is inhibited by I-kappa-B proteinsn(NFKBIA, MIM 164008, or NFKBIB), which inactivate NF-kappa-B byntrapping it in the cytoplasm. Phosphorylation of serine residues onnthe I-kappa-B proteins by kinases (IKBKA, MIM 600664 or IKBKB, MIMn603258) marks them for destruction via the ubiquitination pathway,nthereby allowing activation of the NF-kappa-B complex. ActivatednNFKB complex translocates into the nucleus and binds DNA atnkappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime orn5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or Gnpurine; and Y is a C or T pyrimidine).
- 应用类型
- WB, IHC-P
- 免疫原
- This NFKBIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326-355 amino acids from the C-terminal region of human NFKBIB.
- 来源宿主
- 兔
- 反应性
- 人
- 保存建议
- Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 其他
- ProSci Incorporated于1998年成立于美国加州圣地亚哥市,从事抗体等科研试剂的研发、生产和销售。产品涵盖了细胞凋亡、信号转导、免疫、肿瘤、细胞生物、神经生物、传染病等领域。ProSci拥有超过30000种单克隆抗体和多克隆抗体。ProSci的抗体大都经免疫亲和层析纯化,具有高纯度、高亲和力、特异性强等特点,所有的ProSci抗体都经过了严格的验证测试和质量控制,已保证高质量的产品。此外,ProSci还提供标记二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽等产品与抗体配套使用。

- 注意
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