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中文名称

IL12B 抗体

英文名字
IL12B Antibody
供应商
ProSci
产品货号
PSI-55-192
产品报价
¥询价/400ul
产品说明书
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产品新闻
背景资料
IL12B is a subunit of interleukin 12, a cytokinenthat acts on T and natural killer cells, and has a broad array ofnbiological activities. Interleukin 12 is a disulfide-linkednheterodimer composed of the 40 kD cytokine receptor like subunitnencoded by this gene, and a 35 kD subunit encoded by IL12A. Thisncytokine is expressed by activated macrophages that serve as annessential inducer of Th1 cells development. This cytokine has beennfound to be important for sustaining a sufficient number ofnmemory/effector Th1 cells to mediate long-term protection to annintracellular pathogen. Overexpression of this gene was observed innthe central nervous system of patients with multiple sclerosisn(MS), suggesting a role of this cytokine in the pathogenesis of thendisease. The promoter polymorphism of this gene has been reportednto be associated with the severity of atopic and non-atopic asthmanin children.
应用类型
WB, IHC-P, Flow
免疫原
This IL12B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 264-290 amino acids from the C-terminal region of human IL12B.
来源宿主
反应性
保存建议
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
其他
ProSci Incorporated于1998年成立于美国加州圣地亚哥市,从事抗体等科研试剂的研发、生产和销售。产品涵盖了细胞凋亡、信号转导、免疫、肿瘤、细胞生物、神经生物、传染病等领域。ProSci拥有超过30000种单克隆抗体和多克隆抗体。ProSci的抗体大都经免疫亲和层析纯化,具有高纯度、高亲和力、特异性强等特点,所有的ProSci抗体都经过了严格的验证测试和质量控制,已保证高质量的产品。此外,ProSci还提供标记二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽等产品与抗体配套使用。
注意
该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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