- 中文名称
Tau (phospho Ser416) 抗体
- 英文名字
- Tau (phospho Ser416) Antibody
- 供应商
- ProSci
- 产品货号
- PSI-50-270
- 产品报价
- ¥询价/0.1mL

- 产品说明书
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- 购买方式
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- 产品新闻

- 背景资料
- Tau is a key microtubule-associated protein that plays an important role in the formation of microtubules in axons (Binder et al. 1985). Six tau isoforms have been identified as products of a single gene produced by alternative mRNA splicing (Goedert 1990). Tau mutations have been implicated in many neurodegenerative disorders such as Alzheimer’s disease (AD), Pick’s disease and progressive supranuclear palsy. It has been well documented that hyperphosphorylated tau is a major component of paired helical filaments in AD brain (Lee 1995). Serine 416 has been demonstrated to be a major phosphorylation site in vitro by CaM kinase II (Steiner at al. 1990).
- 应用类型
- WB
- 免疫原
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser416 of rat tau.
- 来源宿主
- 兔
- 反应性
- 人, 小鼠, 大鼠, 牛, 鸡
- 保存建议
- Tau (Ser416) antibody can be stored at -20˚C and is stable at -20˚C for at least 1 year.
- 其他
- ProSci Incorporated于1998年成立于美国加州圣地亚哥市,从事抗体等科研试剂的研发、生产和销售。产品涵盖了细胞凋亡、信号转导、免疫、肿瘤、细胞生物、神经生物、传染病等领域。ProSci拥有超过30000种单克隆抗体和多克隆抗体。ProSci的抗体大都经免疫亲和层析纯化,具有高纯度、高亲和力、特异性强等特点,所有的ProSci抗体都经过了严格的验证测试和质量控制,已保证高质量的产品。此外,ProSci还提供标记二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽等产品与抗体配套使用。

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