- 中文名称
Aquaporin 2 (phospho Ser261) 抗体
- 英文名字
- Aquaporin 2 (phospho Ser261) Antibody
- 供应商
- ProSci
- 产品货号
- PSI-50-225
- 产品报价
- ¥询价/0.1mL

- 产品说明书
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- 产品新闻

- 背景资料
- Aquaporin 2 (AQP2) is a hormonally regulated water channel located in the renal collecting duct. Mutations in the AQP2 gene cause hereditary nephrogenic diabetes insipidus in humans (Iolascon et al.,2007). A vasopressin induced cAMP increase results in the phosphorylation of AQP2 at serine-256 and its translocation from the intracellular vesicles to the apical membrane of principal cells (van Balkom et al., 2002). Recently, serine-261 has been identified as a novel phosphorylation site on AQP2 and levels of phosphorylated S261 have been shown to decrease with vasopressin treatment suggesting its involvement in vasopressin-dependent AQP2 trafficking (Hoffert et al., 2007).
- 应用类型
- WB, IHC
- 免疫原
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser261 of rat aquaporin 2.
- 来源宿主
- 兔
- 反应性
- 人, 小鼠, 大鼠, 狗, 牛, 鸡
- 保存建议
- Aquaporin 2 antibody can be stored at -20˚C and is stable at -20˚C for at least 1 year.
- 其他
- ProSci Incorporated于1998年成立于美国加州圣地亚哥市,从事抗体等科研试剂的研发、生产和销售。产品涵盖了细胞凋亡、信号转导、免疫、肿瘤、细胞生物、神经生物、传染病等领域。ProSci拥有超过30000种单克隆抗体和多克隆抗体。ProSci的抗体大都经免疫亲和层析纯化,具有高纯度、高亲和力、特异性强等特点,所有的ProSci抗体都经过了严格的验证测试和质量控制,已保证高质量的产品。此外,ProSci还提供标记二抗,重组蛋白,细胞和组织裂解液,细胞涂片,组织切片,多肽等产品与抗体配套使用。

- 注意
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