ADP-ribosylation factor-like 14 （ARL14） is a developmentally regulated member of the ADP-ribosylation factor/ARF-like protein （ARF/ARL） family of Ras-related GTPases. ARL14 is GTPase which recruits MYO1E to MHC class II-containing vesicles via the effector protein C11orf46/ARF7EP and thus controls the movement of these vesicles along the actin cytoskeleton in dendritic cells. MHC-II transport was controlled by the GTPase ARL14/ARF7， which recruits the motor myosin 1E via an effector protein ARF7EP.
