GNLY is part of the SAPLIP family and is located in the cytotoxic granules of T cells， which are discharged upon antigen stimulation. GNLY is localized in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells， and it has antimicrobial activity against M. tuberculosis and other organisms. GNLY is an antimicrobial protein that kills intracellular pathogens. GNLY is active against a wide range of microbes， including Gram-positive and Gram-negative bacteria， fungi， and parasites. Kills Mycobacterium tuberculosis.
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大肠杆菌中重组表达
溶解建议
Sterile Filtered White lyophilized （freeze-dried） powder. The Granulysin protein was lyophilized from a concentrated （1mg/ml） solution containing no additives. It is recommended to reconstitute the lyophilized Granulysin in sterile 18MΩ-cm H2O not less than 100ug/ml， which can then be further diluted to other aqueous solutions.
保存建议
Lyophilized Granulysin although stable at room temperature for 3 weeks， should be stored desiccated below -18℃. Upon reconstitution Granulysin should be stored at 4℃ between 2-7 days and for future use below -18℃. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles.
