TRAF1 is an adapter protein and signal transducer that connects members of the TNFR family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. TRAF1 mediates activation of NF-kappa-B and JNK and participates in apoptosis. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2.
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来源宿主
大肠杆菌中重组表达
溶解建议
Sterile filtered colorless solution. TRAF1 Human solution containing 20mM Tris HCL pH-8, 0.1M NaCl, 1mM DTT & 20% glycerol.
保存建议
TRAF1 Human although stable at 4℃ for 1 week, should be stored desiccated below -18℃. Please prevent freeze thaw cycles.