BAG1 binds to BCL2 and is also called BCL2-associated athanogene. BAG1 increases the anti-apoptotic effects of BCL2 and is characterizes as a link between growth factor receptors and anti-apoptotic mechanisms. BAG1 inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. BAG1 inhibits the pro-apoptotic function of PPP1R15A， and has anti-apoptotic activity. BAG1 enhances the anti-cell death function of BCL2 induced by various stimuli.
序列
请咨询我们客服或者请查看品牌官方网站
来源宿主
大肠杆菌中重组表达
溶解建议
Sterile filtered colorless solution. BAG1 Human solution containing 20mM Trsi HCL pH-7.5， 0.1M NaCl and 10% glycerol.
保存建议
BAG1 Human although stable at 4℃ for 1 week， should be stored desiccated below -18℃. Please prevent freeze thaw cycles.
