MAX protein is part of the basic helix-loop-helix leucine zipper （bHLHZ） family of transcription factors. MAX forms homodimers and heterodimers with Mad， Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation， differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site （the E box） and rearrangement among these dimer forms offers a complex system of transcriptional regulation. In contrast to Myc， which is exceedingly regulated throughout progression during the cell cycle， Max is very stable and is much more abundant than Myc.
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大肠杆菌中重组表达
溶解建议
Sterile filtered colorless solution. MAX Human solution containing 20mM Trsi HCL pH-8， 1mM DTT， and 10% glycerol.
保存建议
MAX human although stable at 4℃ for 1 week， should be stored desiccated below -18℃. Please prevent freeze thaw cycles.
