Drosophila that have mutations in their MAGOH gene produce progeny with defects in germplasm assembly and germline development. MAGOH, the human homolog of Drosophila mago nashi, is necessary for embryo development. In mammals, mRNA expression is not limited to the germ plasm, but is expressed ubiquitously in adult tissues and is induced by serum stimulation of quiescent fibroblast.
序列
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来源宿主
大肠杆菌中重组表达
溶解建议
Sterile filtered colorless solution. MAGOH Human solution containing 20mM Trsi HCL pH-8, 2mM DTT, 0.1M NaCl and 20% glycerol.
保存建议
MAGOH Mouse although stable at 4℃ for 1 week, should be stored desiccated below -18℃. Please prevent freeze thaw cycles.