PFN2 is a ubiquitous actin monomer-binding protein which is part of the profilin family. PFN2 regulates actin polymerization in response to extra cellular signals. PFN2 binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, while it increases it at low concentrations. PFN2 binds to PIP2, it inhibits the formation of IP3 and DG.
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来源宿主
大肠杆菌中重组表达
溶解建议
Sterile filtered colorless solution. PFN2 Human solution containing 20mM Trsi HCL pH-8, 1mM DTT and 10% glycerol.
保存建议
PFN2 human although stable at 4℃ for 1 week, should be stored desiccated below -18℃. Please prevent freeze thaw cycles.