Prealbumin is a thyroid hormone-binding protein that transports thyroxine from the bloodstream to the brain. Prealbumin is a carrier protein which transports thyroid hormones in the plasma and cerebrospinal fluid， and also transports retinol （vitamin A） in the plasma. Transthyretin consists of a tetramer of identical subunits and is dominantly produced in the liver. Mutations in Prealbumin are related to amyloid deposition， affecting predominantly peripheral nerve and/or the heart. The diseases caused by mutations include amyloidotic polyneuropathy， euthyroid hyperthyroxinaemia， amyloidotic vitreous opacities， cardiomyopathy， oculoleptomeningeal amyloidosis， meningocerebrovascular amyloidosis， and carpal tunnel syndrome. Prealbumin is an indicator of protein-energy malnutrition since it has a circulating half life of 2 days and reacts swiftly to changes in nutritional status.
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大肠杆菌中重组表达
溶解建议
Sterile filtered colorless solution. The Transthyertin protein solution contains 1x PBS， pH-7.4， and 10% glycerol.
保存建议
Store at 4℃ if entire vial will be used within 2-4 weeks. Store， frozen at -20℃ for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles.
