Alpha 1 ACT is an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin， cathepsin G， and chymase. Alpha-1-ACT， a serine protease inhibitor， is tightly associated with amyloid plaques in Alzheimer’s disease （AD） and in normal aged human and monkey brain.
Regulation of the serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation. Prostate specific antigen （PSA）， a chymotrypsin-like serine protease， is predominantly complexed to Alpha-1-ACT.
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来源宿主
大肠杆菌中重组表达
溶解建议
Sterile Filtered colorless solution. The SERPINA3 solution contains 20mM Tris-HCl buffer pH-8， 1mM DTT， and 10% glycerol.
保存建议
SERPINA3 although stable 4℃ for 4 weeks， should be stored desiccated below -18℃. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles.
