VAMP4 belongs to the synaptobrevin family who are involved in docking and/or fusion of vesicles with cell membrane. VAMP4 is enriched in the trans-Golgi network and may be a factor in the trans-Golgi network-to-endosome transport. VAMP4 is involved in the pathway which functions to eliminate an inhibitor （most likely synaptotagmin-4） of calcium-triggered exocytosis during the maturation of secretory granules. Synaptobrevins， syntaxins， and SNAP25 are the chief components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane.
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来源宿主
大肠杆菌中重组表达
溶解建议
Sterile filtered colorless solution. The VAMP4 protein solution contains 20mM Tris-HCl buffer （pH 8.0）， 0.1M NaCl， and 20% glycerol.
保存建议
Store at 4℃ if entire vial will be used within 2-4 weeks.
Store， frozen at -20℃ for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles.
