Ferredoxin-1 is a small iron-sulfur protein who transfers electrons from NADPH through ferredoxin reductase to a terminal cytochrome P450. This specific oxidation/reduction system is located in steroidogenic tissues， and is involved with the synthesis of bile acid and vitamin D. FDX1 takes part in the synthesis of thyroid hormones and transfers electrons from adrenodoxin reductase to the cholesterol side chain cleavage cytochrome P450. FDX1 supports reactions catalyzed by human microsomal P450s- full length CYP17， truncated CYP17， and truncated CYP21. In addition to the FDX1 at the 11q22chromosomal locus， there are pseudogenes located on chromosomes 20 and 21.
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来源宿主
大肠杆菌中重组表达
溶解建议
Sterile Filtered colorless solution. The FDX1 solution contains 20mM Tris-HCl buffer （pH8.0） and 10% Glycerol.
保存建议
FDX1 although stable 4℃ for 4 weeks， should be stored desiccated below -18℃. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles.
