PTX3 is part of the pentraxin family sharing the C-terminal domain with short pentraxins and containing a unique N-terminal domain. PTX3 is produced and released at inflammatory sites by various cell types including monocytes/macrophages， endothelial cells， vascular smooth muscle cells， fibroblasts， and adipocytes. PTX3 is involved in the regulation of innate resistance to pathogens， inflammatory reactions， possibly clearance of self-components and female fertility. PTX3 is used as a marker for disease activity of psoriasis. High serum PTX3 levels are associated with the disease severity of systemic sclerosis. Elevated serum PTX3 is associated with pulmonary fungal infections.
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来源宿主
大肠杆菌中重组表达
溶解建议
Sterile filtered colorless solution. The PTX3 protein contains 20mM Tris-HCl buffer pH-8.5， 1mM DTT and 10% glycerol.
保存建议
Store at 4℃ if entire vial will be used within 2-4 weeks.
Store， frozen at -20℃ for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles.
