Chromgranin-A is part of the neuroendocrine secretory protein family. CHGA is located in secretory vesicles of neurons and endocrine cells. Chromgranin-A is a precursor to three biologically active peptides； vasostatin， pancreastatin， and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides， including chromostatin， beta-granin， WE-14 and GE-25， are also derived from the full-length protein. Chromgranin-A has numerous biological activities on some tissues and organs and exerts a large spectrum of homeostatic actions， including antifungal and antimicrobial effect， modulation of cell adhesion， and inhibition of parathyroid hormone secretion.
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来源宿主
大肠杆菌中重组表达
溶解建议
Sterile filtered colorless solution. The CHGA protein contains 20mM Tris-HCl buffer pH-8， and 10% glycerol.
保存建议
Store at 4℃ if entire vial will be used within 2-4 weeks.
Store， frozen at -20℃ for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles.
