WIF1 binds to wnt proteins and inhibits their activities. WIF1 plays a role in mesoderm segmentation. WNT proteins are extracellular signaling molecules that take part in the control of embryonic development & cancer. WIF1 protein contains a WNT inhibitory factor （WIF） domain and 5 epidermal growth factor （EGF）-like domains. WIF1 takes part in mesoderm segmentation. WIF1 protein is found to be present in fish， amphibia and mammals. WIF1 is a recurrent target in human salivary gland oncogenesis. Downregulation of WIF1 takes part in the development and progression of pleomorphic adenomas. WIF1 is a tumor suppressor， specifically in nonfunctioning pituitary tumors.
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来源宿主
昆虫His-5细胞中重组表达
溶解建议
Sterile filtered colorless solution. The WIF1 protein solution contains 1X PBS pH 7.4， 10% glycerol and 1mM PMSF.
保存建议
Store at 4℃ if entire vial will be used within 2-4 weeks.
Store， frozen at -20℃ for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles.
