VAMP8 also called endobrevin， is the main component of a SNARE complex involved in the docking and fusion of synaptic vesicles with the presynaptic membrane. VAMP8 protein is involved in the regulatation of enzyme secretion in pancreatic acinar cells and plays a part in the abscission of the midbody during cell division， which leads to completely separate daughter cells. VAMP8 is essential for dense-granule secretion in platelets. VAMP8 is related with the perinuclear vesicular structures of the early endocytic compartment. VAMP8 interacts particularly with the soluble NSF-attachment protein （alpha-SNAP）， through an VAMP8-containing SNARE complex.
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来源宿主
大肠杆菌中重组表达
溶解建议
Sterile Filtered colorless solution. The VAMP8 protein solution contains 20mM Tris pH-8 and 30% glycerol.
保存建议
VAMP8 although stable 4℃ for 4 weeks， should be stored desiccated below -18℃.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles.
