CRABP2 NCBI Accession No: NP_001869 regulates the access of retinoic acid to the nuclear retinoic acid receptors. CRABP2 is involved in a regulatory feedback mechanism that controls the action of retinoic acid on cell differentiation.
CRABP2 is involved in the conversion of vitamin A into its intracellular active form retinoic acid， which regulate the genes responsible for lipid metabolism and adipocyte differentiation. CRABP2 gene is located on chromosome 1q21-23 and this region has been linked with related disorders such as familial combined hyperlipidemia （FCHL） and type 2 diabetes mellitus.
CRABP proteins are of low molecular weight having an important function in retinoic acid-mediated regulation of human skin growth and differentiation.
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大肠杆菌中重组表达
溶解建议
Sterile Filtered colorless solution. The CRABP2 protein solution contains 20mM Tris-HCl pH-8 and 20% glycerol.
保存建议
CRABP2 although stable 4℃ for 4 weeks， should be stored desiccated below -18℃.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles.
