RND3 is a small GTPase which is part of the Ras superfamily that controls the association of the actin cytoskeleton in reaction to extracellular growth factors. RND3 activity causes a decrease in stress fibers and an increase in cell migration， at least in part through regulation of the Rho-dependent kinase ROCK1. RND3 inhibits DNA-damage induced apoptosis and cell cycle arrest. RND3 binds GTP and is resistant to Rho-specific GTPase-activating proteins.
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来源宿主
大肠杆菌中重组表达
溶解建议
Sterile filtered colorless solution. RND3 Human solution containing 20mM Tris pH-8， 1mM DTT， 0.1M NaCl & 40% glycerol.
保存建议
RND3 Human although stable at 4℃ for 1 week， should be stored desiccated
below -18℃.
Please prevent freeze thaw cycles.
